The EDAR Antibody (CAB4461) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly sensitive and reacts specifically with human samples, making it a reliable tool for Western blot applications. By binding to the EDAR protein, this antibody enables the detection and analysis of EDAR in various cell types, making it ideal for studies in developmental biology and dermatology.EDAR, or Ectodysplasin A receptor, is known for its role in the development of ectodermal tissues, including hair, teeth, and sweat glands. Understanding the function of EDAR is essential for unraveling the mechanisms underlying ectodermal development and related disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
EDAR Antibody
SKU:
CAB4461
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Purification Method
Affinity purification
Gene ID
10913
RRID
AB_2765691
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using EDAR Rabbit pAb (CAB4461) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
