The EDNRB Antibody (CAB2908) is a high-quality antibody developed for reliable detection and analysis of target proteins. EDNRB is a G-protein coupled receptor involved in the regulation of blood pressure, cell proliferation, and migration.This polyclonal antibody, produced in rabbits, has high reactivity with human samples and is specifically validated for use in Western blot applications. It binds to the EDNRB protein, allowing for accurate detection and analysis in a variety of cell types. This makes it an ideal choice for studies in cardiovascular biology, cancer research, and developmental biology.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
EDNRB Antibody
SKU:
CAB2908
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
1910
RRID
AB_2764727
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using EDNRB Rabbit pAb (CAB2908) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
