The EGFL8 Polyclonal Antibody (PACO14367) is a valuable tool for researchers studying EGFL8, a protein involved in various biological processes including cell adhesion, migration, and angiogenesis. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting EGFL8 in human samples, making it ideal for experiments such as Western blotting.EGFL8, also known as MAM domain-containing protein 4, plays a crucial role in the regulation of cell behavior and signaling pathways involved in cancer progression and metastasis.
By targeting EGFL8, researchers can gain insights into the mechanisms underlying these processes and potentially uncover new therapeutic targets for cancer treatment.The availability of a reliable antibody like PACO14367 enables researchers to explore the functions of EGFL8 in various cellular contexts, advancing our understanding of its role in cancer development and progression. With its versatility and specificity, this antibody is a valuable asset for studies in cancer research and beyond.
Antibody Name:
EGFL8 Antibody (PACO14367)
Antibody SKU:
PACO14367
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human EGFL8
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO14367(EGFL8 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14367(EGFL8 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion, and neural and vertebrate development. EGFL8 (EGF-like domain-containing protein 8), also known as C6orf8, NG3 and VE-statin-2, is a 293 amino acid, secreted protein that contains two EGF-like domains and one EMI domain. Via its EGF and EMI domains, EGFL8 may participate in protein-protein interactions that correlate with cellular proliferation and developmental signaling events. In mice, EGFL8 is expressed predominately in brain, kidney, lung and thymus.
Synonyms:
EGF-like-domain, multiple 8
UniProt Protein Function:
EGFL8: Protein type: Calcium-binding; Membrane protein, integral; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 6p21.32Cellular Component: extracellular regionMolecular Function: calcium ion bindingBiological Process: in utero embryonic development
