The ELL Polyclonal Antibody (CAB16449) is a valuable tool for researchers studying the ELL protein, which is involved in RNA polymerase II transcription. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ELL protein, this antibody enables researchers to detect and analyze ELL expression in various cell types.ELL, also known as eleven-nineteen lysine-rich leukemia, plays a crucial role in transcription elongation and regulation of gene expression.
Dysregulation of ELL has been implicated in various diseases, including leukemia and other cancers. Studying the function and expression of ELL is key to understanding its role in these diseases and developing potential targeted therapies.Overall, the ELL Polyclonal Antibody (CAB16449) is a valuable tool for researchers in the fields of molecular biology, cancer research, and genetics, providing insights into the role of ELL in transcription and its implications for disease pathology.
Product Name:
ELL Rabbit Polyclonal Antibody
SKU:
CAB16449
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human ELL (NP_006523.1).
Enables phosphatase binding activity. Involved in positive regulation of transcription, DNA-templated and snRNA transcription. Located in cytosol; nuclear body; and transcriptionally active chromatin. Part of transcription elongation factor complex.
Purification Method:
Affinity purification
Gene ID:
8178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ELL Rabbit pAb (CAB16449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
