The Enox2 Monoclonal Antibody (CAB21967) is a vital tool for researchers studying Enox2, a protein involved in DNA repair and cell survival pathways. This antibody, produced through hybridoma technology, is highly specific to Enox2 and has been validated for use in various experimental applications such as immunofluorescence and immunohistochemistry.Enox2, also known as APE2, is a critical component in the base excision repair pathway that helps maintain genomic integrity and overall cell health. Dysregulation of Enox2 has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
With the Enox2 Monoclonal Antibody, researchers can effectively study the expression and localization of Enox2 in different cell types and tissues, providing valuable insights into its function and potential implications in disease progression. This antibody is a valuable tool for advancing research in the fields of cancer biology, DNA repair mechanisms, and targeted therapies.
Product Name:
ENOX2 Monoclonal Antibody
SKU:
CAB21967
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 411-610 of human ENOX2 (NP_872114.1).
This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10495
Clone Number:
ARC53634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of MCF7 cells, using ENOX2 antibody (CAB21967) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:200000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
