The ERO1LB Polyclonal Antibody (CAB3682) is a valuable tool for researchers studying ERO1LB, an enzyme involved in oxidative protein folding in the endoplasmic reticulum. This antibody, produced using rabbits as a host species, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ERO1LB protein, this antibody allows for the detection and analysis of ERO1LB in various cell types, making it an essential component for studies in biochemistry and cell biology.
ERO1LB plays a crucial role in protein folding and redox balance within the ER, making it a key player in maintaining cellular homeostasis. Dysregulation of ERO1LB has been implicated in various diseases, including neurodegenerative disorders, diabetes, and cancer, highlighting the importance of understanding its function. By studying ERO1LB, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
ERO1LB Rabbit Polyclonal Antibody
SKU:
CAB3682
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 34-230 of human ERO1LB (NP_063944.3).
Enables thiol oxidase activity. Involved in protein folding in endoplasmic reticulum. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane.
Purification Method:
Affinity purification
Gene ID:
56605
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ERO1LB antibody (CAB3682) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
