The EXOSC7 Antibody (CAB9689) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting Exosc7 in human samples, making it ideal for Western blot applications.Exosc7 plays a key role in maintaining RNA stability and quality control, making it essential for cellular function and gene expression regulation. Dysregulation of Exosc7 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in biological processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
EXOSC7 Antibody
SKU:
CAB9689
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
p8, EAP1, RRP42, Rrp42p, hRrp42p, EXOSC7
Positive Sample:
U-87MG, SKOV3, K-562, Jurkat, MCF7, Mouse brain, Rat brain
Cellular Localization:
Cytoplasm, Nucleus, Nucleolus.
Calculated MW:
32kDa
Observed MW:
37kDa
Predicted to enable 3'-5'-exoribonuclease activity and RNA binding activity. Predicted to be involved in RNA metabolic process. Part of exosome (RNase complex).
Purification Method
Affinity purification
Gene ID
23016
RRID
AB_2769382
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXOSC7 Rabbit pAb (CAB9689) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
