The EXOSC8 Antibody (CAB4507) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through the immunization of rabbits, exhibits high specificity and sensitivity in detecting ExoSC8 in human samples, making it ideal for Western blot applications. By targeting the ExoSC8 protein, researchers can gain valuable insights into exosome biogenesis and its role in intercellular signaling pathways.Exosomes are small vesicles released by cells that play a critical role in cell-to-cell communication and the transfer of biomolecules. ExoSC8, as a component of the exosome secretion machinery, is essential for the proper formation and release of exosomes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
EXOSC8 Antibody
SKU:
CAB4507
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
Purification Method
Affinity purification
Gene ID
11340
RRID
AB_2765723
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using EXOSC8 Rabbit pAb (CAB4507) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
