The XPOT Antibody (CAB12043) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting Exportin-T, researchers can analyze its role in nucleocytoplasmic transport and gene expression regulation, particularly in cancer and developmental biology studies.Exportin-T is a key player in transporting RNA molecules and proteins out of the nucleus, making it essential for cellular function and gene expression control.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
XPOT Antibody
SKU:
CAB12043
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
XPO3, XPOT
Positive Sample:
B cells, Mouse brain, Mouse kidney, Mouse liver, Rat kidney
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
110kDa
Observed MW:
100kDa
This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.
Purification Method
Affinity purification
Gene ID
11260
RRID
AB_2758954
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using XPOT Rabbit pAb (CAB12043) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
