The EXTL2 Polyclonal Antibody (CAB15669) is a valuable tool for researchers studying the role of EXTL2, a protein involved in the biosynthesis of heparan sulfate, a key component of the extracellular matrix. This antibody, produced in rabbit hosts, is highly specific to human samples and has been validated for use in Western blot applications.EXTL2 is known for its essential role in the regulation of cell proliferation, differentiation, and adhesion, making it a promising target for research in developmental biology, cancer biology, and tissue regeneration studies.
This antibody binds specifically to the EXTL2 protein, enabling precise detection and analysis in a variety of cell types.By using the EXTL2 Polyclonal Antibody, researchers can gain a better understanding of the molecular mechanisms underlying heparan sulfate biosynthesis and its involvement in various physiological and pathological processes. This antibody is an invaluable tool for advancing knowledge in the fields of glycobiology and extracellular matrix biology.
Product Name:
EXTL2 Rabbit Polyclonal Antibody
SKU:
CAB15669
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 41-330 of human EXTL2 (NP_001430.1).
Endoplasmic reticulum membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
37kDa
Observed MW:
37kDa
Enables alpha-1,4-N-acetylgalactosaminyltransferase activity and glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Involved in N-acetylglucosamine metabolic process and UDP-N-acetylgalactosamine metabolic process. Located in cytosol; endoplasmic reticulum; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
2135
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EXTL2 Rabbit pAb (CAB15669) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
