The FAF1 Antibody (CAB2921) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit immunization, is highly specific to human samples and has been validated for use in Western blot applications.FAF1, also known as Fas-associated factor 1, is a crucial regulator of apoptosis and cell growth, making it a target of interest in cancer research and molecular biology. By binding to the FAF1 protein, this antibody enables researchers to detect and analyze FAF1 expression in different cell types, allowing for insights into its functions and interactions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
FAF1 Antibody
SKU:
CAB2921
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
hFAF1, CGI-03, HFAF1s, UBXD12, UBXN3A, FAF1
Positive Sample:
OVCAR3, HT-29, Mouse brain, Mouse liver, Rat brain
Cellular Localization:
Nucleus.
Calculated MW:
74kDa
Observed MW:
85kDa
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
Purification Method
Affinity purification
Gene ID
11124
RRID
AB_2764739
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FAF1 Rabbit pAb (CAB2921) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
