The FAM129A Polyclonal Antibody (PAC022987) is a valuable tool for researchers studying FAM129A, a protein involved in cell signaling and apoptosis regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By targeting the FAM129A protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an excellent choice for studies in cell biology and cancer research.FAM129A, also known as Niban, plays a key role in regulating cell growth and survival pathways, making it a promising target for investigating various diseases, including cancer and neurodegenerative disorders.
Understanding the function of FAM129A is essential for identifying potential therapeutic targets and developing novel treatment strategies in these disease contexts.Overall, the FAM129A Polyclonal Antibody (PAC022987) offers researchers a reliable tool for investigating the role of FAM129A in cell signaling pathways and its potential implications in disease pathogenesis. Its specificity and sensitivity make it an ideal choice for experiments aiming to elucidate the molecular mechanisms underlying FAM129A function.
peptide sequence around aa. 912~916 (K-E-G-E-G) derived from Human Niban.
Form:
Liquid
Storage Buffer:
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from A431 and DU145 cells using Niban Antibody.
Immunofluorescence staining of methanol-fixed Hela cells using Niban Antibody.
Background:
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response
Synonyms:
FAM129A
UniProt Protein Function:
FAM129A: Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response. Belongs to the Niban family.
Biological Process: negative regulation of protein amino acid phosphorylation; positive regulation of translation; positive regulation of protein amino acid phosphorylation
