Description
FANCG Rabbit Polyclonal Antibody (CAB6206)
The FANCG Polyclonal Antibody (CAB6206) is a valuable tool for research studies involving FANCG, a key protein involved in the Fanconi Anemia pathway. This antibody, generated in rabbits, exhibits strong reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the FANCG protein, researchers can easily detect and analyze its expression in various cell types, making it an ideal choice for investigations in the fields of genetics and cancer research.FANCG plays a crucial role in maintaining genome stability and DNA repair processes, making it a critical factor in the prevention of cancer and other genetic disorders.
By studying the function and regulation of FANCG, researchers can gain valuable insights into the mechanisms underlying these conditions, potentially leading to the development of novel therapeutic strategies.Overall, the FANCG Polyclonal Antibody (CAB6206) offers a reliable and specific tool for researchers interested in unraveling the complex biology of FANCG and its implications for human health. Its versatility and accuracy make it a valuable asset in the pursuit of advancing our understanding of genetic disorders and cancer development.
| Product Name: | FANCG Rabbit Polyclonal Antibody |
| SKU: | CAB6206 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 343-622 of human FANCG (NP_004620.1). |
| Sequence: | QSQT KHIL ASRC LQTG RAGD AAEH YLDL LALL LDSS EPRF SPPP SPPG PCMP EVFL EAAV ALIQ AGRA QDAL TLCE ELLS RTSS LLPK MSRL WEDA RKGT KELP YCPL WVSA THLL QGQA WVQL GAQK VAIS EFSR CLEL LFRA TPEE KEQG AAFN CEQG CKSD AALQ QLRA AALI SRGL EWVA SGQD TKAL QDFL LSVQ MCPG NRDT YFHL LQTL KRLD RRDE ATAL WWRL EAQT KGSH EDAL WSLP LYLE SYLS WIRP SDRD AFLE EFRT SLPK SCDL |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:2000 |
| Synonyms: | FAG; XRCC9; FANCG |
| Positive Sample: | THP-1,U-251MG,HeLa,HepG2,MCF7,Mouse liver |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Nucleus. |
| Calculated MW: | 69kDa |
| Observed MW: | 69kDa |
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
| Purification Method: | Affinity purification |
| Gene ID: | 2189 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
 | Western blot analysis of extracts of various cell lines, using FANCG antibody (CAB6206) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 50s. |
