The FAU Polyclonal Antibody (PAC046118) is a vital tool for researchers studying FAU, a critical protein associated with cell growth and proliferation. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used with human samples, making it a reliable choice for Western blot applications. By targeting the FAU protein, this antibody enables precise detection and analysis across various cell types, facilitating investigations in fields such as cancer biology and molecular biology.FAU, also known as Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed gene, plays a crucial role in cell cycle regulation and is frequently upregulated in cancer cells.
Understanding the functions and regulation of FAU is essential for unraveling its involvement in tumorigenesis and cancer progression. The FAU Polyclonal Antibody provides researchers with a valuable tool to explore the mechanisms underlying FAU's role in cellular processes, paving the way for potential therapeutic interventions targeting FAU in cancer treatment.
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO46118 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO46118 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human colon cancer using PACO46118 at dilution of 1:100.
Synonyms:
40S ribosomal protein S30 (Small ribosomal subunit protein eS30), FAU
UniProt Protein Function:
RPS30: This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin. [provided by RefSeq, Jul 2008]Protein type: Ribosomal; Translation; ApoptosisChromosomal Location of Human Ortholog: 11q13
UniProt Protein Details:
NCBI Summary:
This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome and displays antimicrobial activity. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin. [provided by RefSeq, Nov 2014]
