The FEM1A Polyclonal Antibody (CAB16129) is a powerful tool for researchers studying FEM1A, a protein involved in cell cycle regulation and apoptosis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the FEM1A protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for studies in oncology and cell biology.FEM1A, also known as FEM1A ubiquitin ligase, plays a crucial role in controlling cell division and programmed cell death pathways.
Its involvement in these fundamental cellular processes makes it a key target for investigation in cancer research and drug development. Understanding the function of FEM1A can provide valuable insights into the mechanisms of tumorigenesis and potential therapeutic interventions aimed at targeting this pathway. Researchers looking to explore the role of FEM1A in disease progression and treatment strategies will find the CAB16129 antibody to be a valuable asset in their studies.
Product Name:
FEM1A Rabbit Polyclonal Antibody
SKU:
CAB16129
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human FEM1A (NP_061178.1).
Enables EP4 subtype prostaglandin E2 receptor binding activity and ubiquitin ligase-substrate adaptor activity. Involved in negative regulation of inflammatory response and ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Part of Cul2-RING ubiquitin ligase complex. Is active in mitochondrion.
Purification Method:
Affinity purification
Gene ID:
55527
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FEM1A Rabbit pAb (CAB16129) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
