The FGF6 Polyclonal Antibody (PAC020995) is a valuable tool for researchers studying FGF6, a member of the fibroblast growth factor (FGF) family with important roles in development and tissue repair. This antibody, produced in rabbits, is highly specific to FGF6 in human samples and has been validated for use in Western blot applications. By binding to the FGF6 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for investigations in developmental biology and tissue regeneration.FGF6 is known to promote cell proliferation, migration, and differentiation in various tissues, making it a key player in processes such as wound healing and organogenesis.
Understanding the functions and regulation of FGF6 is crucial for unraveling its therapeutic potential in conditions such as tissue injuries, developmental abnormalities, and certain cancers. The FGF6 Polyclonal Antibody provides researchers with a reliable tool to explore the roles of FGF6 in these contexts, ultimately contributing to advancements in regenerative medicine and cancer treatment.
Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane: Human fetal muscle tissue, Primary antibody: PACO20995(FGF6 Antibody) at dilution 1/300 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20995(FGF6 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells.
Synonyms:
fibroblast growth factor 6
NCBI Summary:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008]
