The FHOD1 Polyclonal Antibody (CAB15438) is a crucial tool for researchers studying FHOD1, a protein involved in actin cytoskeleton dynamics and cell shape regulation. This antibody, derived from rabbits, exhibits high specificity for FHOD1 in human samples and is validated for use in Western blot applications. By binding to FHOD1, it enables precise detection and analysis of this protein in various cell types, making it essential for studies in cell biology and cancer research.
FHOD1 is known for its role in controlling actin filament assembly and organization, which is essential for maintaining cell structure and function. Dysregulation of FHOD1 has been linked to various diseases, including cancer and developmental disorders. Therefore, investigating the function of FHOD1 using this antibody is crucial for understanding its implications in disease pathology and developing potential therapeutic interventions.
Product Name:
FHOD1 Rabbit Polyclonal Antibody
SKU:
CAB15438
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1010-1120 of human FHOD1 (NP_037373.2).
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29109
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using FHOD1 Rabbit pAb (CAB15438) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
