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Key Features

FITC Anti-Human CD193/CCR3 Antibody [5E8] (AGEL3402)

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SKU AGEL3402
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, k
Clone [5E8]
Conjugation FITC
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Description

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FITC Anti-Human CD193/CCR3 Antibody [5E8]

The FITC Anti-Human CD193 (CCR3) Antibody (5E8) offered by AssayGenie is a highly specialized tool designed for researchers studying the CD193 (CCR3) protein, a cell surface receptor involved in inflammatory responses and allergic reactions. This antibody, optimized for use in flow cytometry and immunofluorescence applications, specifically targets the CD193 (CCR3) molecule in human samples with high accuracy and sensitivity.CD193 (CCR3) is a critical receptor implicated in allergic diseases, asthma, and inflammation, making it a key target for research in immunology and respiratory conditions. By using the FITC Anti-Human CD193 (CCR3) Antibody (5E8), researchers can effectively detect and analyze the expression and localization of CD193 (CCR3) in various cell types, providing valuable insights into its role in immune responses and disease pathogenesis.

With its superior specificity and performance in experimental settings, this antibody enables precise and reliable detection of CD193 (CCR3), facilitating detailed investigation into its signaling pathways and potential therapeutic implications. Researchers can leverage the unique capabilities of this antibody to advance their studies in allergy, asthma, and inflammatory disorders, ultimately contributing to the development of novel treatment strategies and improved patient outcomes.

Product Title:FITC Anti-Human CD193/CCR3 Antibody [5E8]
SKU:AGEL3402
Size:20 Tests, 100 Tests, 200 Tests
Clone No:5E8
Synonyms:CC CKR3; MIP1-alpha receptor like-2; eotaxin receptor;CCR;C-C chemokine receptor type 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:FITC Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P51677
Gene ID:1232
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

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