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FITC Anti-Mouse CD3 Antibody [17A2] (AGEL2151)

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SKU AGEL2151
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone 17A2
Conjugation FITC
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Description

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FITC Anti-Mouse CD3 Antibody [17A2]

The FITC Anti-Mouse CD3 Antibody (17A2) available at assaygenie.com is a vital tool for researchers studying immune responses in mice. This antibody, specifically designed for use in flow cytometry and immunofluorescence applications, targets the CD3 protein present on T cells. By binding to CD3, this antibody enables the precise detection and analysis of T cells in a variety of experimental settings.CD3 is an essential component of the T cell receptor complex and plays a crucial role in T cell activation and function. Understanding the dynamics of CD3 expression and localization is fundamental to unraveling the complexities of immune responses and developing novel immunotherapies.

The FITC Anti-Mouse CD3 Antibody (17A2) offers high specificity and sensitivity, making it a reliable tool for investigating T cell biology in both basic research and preclinical studies.Researchers interested in studying T cell function, immune disorders, or vaccine development will find the FITC Anti-Mouse CD3 Antibody (17A2) from assaygenie.com to be a valuable addition to their experimental arsenal. With its proven performance and broad reactivity in mouse samples, this antibody provides insights into the intricate mechanisms governing T cell responses, paving the way for advancements in immunology research and therapeutic interventions.

Product Title:FITC Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL2151
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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