Description
FITC-Labeled Recombinant Human B7-H3/CD276 Protein
The FITC-Labeled Recombinant Human B7-H3/CD276 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating FITC-Labeled B7-H3/CD276 function and its implications in health and disease.
This product (SKU: RPCB0700) is produced using advanced expression systems and features a C-hFc tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 50.1 kDa with an observed molecular weight of 65-70 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography | |
Mammalian & Bacterial Expression Systems | |
High lot-to-lot consistency via strict QC |
Product Name: | FITC-Labeled Recombinant Human B7-H3/CD276 Protein |
SKU: | RPCB0700 |
Size: | 100 μg |
Reactivity: | Human |
Synonyms: | B7H3, B7-H3, CD276, PSEC0249, UNQ309, PRO352, B7 homolog 3, CD276 |
Tag: | C-hFc |
Calculated MW: | 50.1 kDa |
Observed MW: | 65-70 kDa |
Gene ID: | 80381 |
Protein Description: | High quality, high purity and low endotoxin recombinant FITC-Labeled Recombinant Human B7-H3/CD276 Protein (RP00635FLQ), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 1 EU/μg of the protein by LAL method. |
Purity: | ≥ 95 % as determined by SDS-PAGE. |
Formulation: | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig?B7?H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.