The FIZ1 Antibody (PAC013438) is a polyclonal antibody designed for research involving FIZ1, a zinc finger protein that plays a critical role in gene regulation and transcriptional control. The antibody, raised in rabbits, is highly specific to FIZ1 and is validated for use in various applications, including immunohistochemistry and immunofluorescence.FIZ1 is known to interact with various proteins involved in chromatin remodeling and gene expression, making it a key player in cellular processes such as cell differentiation and proliferation. Its relevance in cancer research is particularly notable, as dysregulation of FIZ1 has been linked to tumorigenesis and metastasis in various types of cancer.
Furthermore, FIZ1 has been implicated in other diseases, including neurological disorders and developmental abnormalities, highlighting its potential as a therapeutic target for a range of conditions. Understanding the function and regulation of FIZ1 is crucial for advancing our knowledge of cellular processes and disease mechanisms, making the FIZ1 Antibody a valuable tool for researchers in molecular biology and related fields.
FIZ1: May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.42Cellular Component: cytoplasm; nucleusMolecular Function: receptor tyrosine kinase binding
UniProt Protein Details:
NCBI Summary:
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008]
