The FMN2 Polyclonal Antibody (PACO09319) is a valuable tool for researching FMN2, a protein associated with cellular structures and functions. This antibody, produced in rabbits, exhibits high reactivity with human samples, making it suitable for use in Western blot applications. By binding specifically to the FMN2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology, molecular biology, and related fields.
FMN2, also known as Formin 2, is essential for the organization of the cytoskeleton and plays a crucial role in cell migration, cell division, and other cellular processes. Its involvement in cellular dynamics makes it a promising target for research on cancer, developmental biology, and neurobiology. Understanding the function of FMN2 is key to unraveling its roles in health and disease, paving the way for potential therapeutic interventions targeting this protein.
FMN2: Belongs to the formin homology family. Cappuccino subfamilyProtein type: Nucleolus; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 1q43Cellular Component: endoplasmic reticulum membrane; cytoplasmic vesicle membrane; microvillus; perinuclear region of cytoplasm; plasma membrane; nucleolus; spindle; cell cortex; cytosol; actin cytoskeletonMolecular Function: actin bindingBiological Process: oogenesis; vesicle-mediated transport; homologous chromosome movement towards spindle pole during meiosis I; establishment of meiotic spindle localization; protein transport; intracellular transport; multicellular organismal development; polar body extrusion after meiotic divisions; negative regulation of protein catabolic process; response to DNA damage stimulus; negative regulation of apoptosisDisease: Mental Retardation, Autosomal Recessive 47
UniProt Protein Details:
NCBI Summary:
Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.[supplied by OMIM, Apr 2010]
