The FN3K Polyclonal Antibody (CAB13727) is a valuable tool for researchers studying FN3K, a key enzyme involved in the regulation of glucose metabolism and diabetic complications. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and is optimized for Western blot applications.FN3K, also known as Fructosamine-3-kinase, plays a crucial role in the metabolism of advanced glycation end products (AGEs) and fructosamines, which are involved in the pathogenesis of diabetes and related complications.
By targeting FN3K, researchers can better understand its role in diabetic complications such as nephropathy, neuropathy, and retinopathy.The FN3K Polyclonal Antibody is an essential tool for studying the function and regulation of FN3K in various biological samples, making it ideal for research focused on diabetes, metabolic disorders, and related complications. Its specificity and sensitivity ensure reliable results, providing valuable insights into the molecular mechanisms underlying these conditions.
Product Name:
FN3K Rabbit Polyclonal Antibody
SKU:
CAB13727
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FN3K (NP_071441.1).
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation.
Purification Method:
Affinity purification
Gene ID:
64122
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FN3K Rabbit pAb (CAB13727) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
