The FOLH1B Polyclonal Antibody (PAC019673) is a vital tool for researchers studying FOLH1B, a cell surface receptor involved in tumor progression and metastasis. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it a reliable choice for Western blot applications. By binding to the FOLH1B protein, this antibody enables precise detection and analysis in diverse cell types, making it well-suited for investigations in oncology and cancer biology.FOLH1B, also known as prostate-specific membrane antigen (PSMA), plays a crucial role in tumor cell survival and proliferation, making it a promising target for cancer therapy development.
Understanding the function of FOLH1B is essential for advancing research into novel treatments for prostate cancer and other malignancies. By utilizing the FOLH1B Polyclonal Antibody in their studies, researchers can gain valuable insights into the mechanisms underlying tumor growth and metastasis, paving the way for the development of targeted therapies that exploit the vulnerabilities of cancer cells.
Antibody Name:
FOLH1B Antibody (PACO19673)
Antibody SKU:
PACO19673
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human FOLH1B
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19673(FOLH1B Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO19673(FOLH1B Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
PSM is an integral membrane protein, and PCTA-1 is related to the galectin gene family, which mediate both cell-cell and cell-matrix interactions in a manner similar to the selectin subgroup of C-type lectins. STEAP is a serpentine transmembrane cell-surface tumor-antigen that is predicted to functions as a channel or transporter protein. In addition to prostate cancers, STEAP is also upregulated in bladder, colon and ovarian cancers.
Synonyms:
folate hydrolase 1B
UniProt Protein Function:
PSMAL: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Belongs to the peptidase M28 family. M28B subfamily.Protein type: EC 3.4.-.-Chromosomal Location of Human Ortholog: 11q14.3Cellular Component: plasma membraneMolecular Function: dipeptidase activity; metallocarboxypeptidase activityBiological Process: amino acid biosynthetic process
