The FOXD4 Antibody (PAC017891) is a valuable tool for researchers studying FOXD4, a transcription factor involved in regulating gene expression and development. This polyclonal antibody, raised in rabbits, is highly specific and reactive with human samples, making it suitable for a range of applications including Western blot and immunohistochemistry.FOXD4 is known to play a role in various cellular processes such as cell proliferation, differentiation, and migration, making it a key player in developmental biology and cancer research.
By targeting FOXD4 with this antibody, researchers can gain insights into its functions and regulatory mechanisms, paving the way for potential therapeutic interventions in diseases where FOXD4 dysregulation is implicated. Overall, the FOXD4 Antibody (PAC017891) is a reliable tool for investigating the role of FOXD4 in normal development and disease pathogenesis, offering valuable insights into potential therapeutic targets and treatment strategies.
Antibody Name:
FOXD4 Antibody (PACO17891)
Antibody SKU:
PACO17891
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human FOXD4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: PACO17891(FOXD4 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
Background:
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality.
Synonyms:
forkhead box D4
UniProt Protein Function:
FOXD4: Protein type: Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 9p24.3Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity; DNA bending activityBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality. [provided by RefSeq, Mar 2012]
