The FOXF2 Polyclonal Antibody (PAC017875) is a valuable tool for researchers studying the FOXF2 protein, a transcription factor involved in embryonic development and tissue homeostasis. This antibody is produced in rabbits and has been validated for use in various applications, including Western blotting, immunofluorescence, and immunohistochemistry.FOXF2 plays a key role in regulating gene expression and cell differentiation, making it an important target for investigations into developmental biology and disease mechanisms. Its dysregulation has been linked to various cancers, including breast and prostate cancer.
By using the FOXF2 Polyclonal Antibody, researchers can gain insights into the functions and regulation of this protein in different cell types and tissues.Overall, the FOXF2 Polyclonal Antibody is a versatile tool that can enhance research efforts in areas such as cancer biology, stem cell research, and tissue regeneration. Its high reactivity and specificity make it a reliable choice for detecting and analyzing FOXF2 expression in experimental settings.
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO17875(FOXF2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: PACO17875(FOXF2 Antibody) at dilution 1/733, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17875(FOXF2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.
Synonyms:
forkhead box F2
UniProt Protein Function:
FOXF2: Probable transcription activator for a number of lung- specific genes.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 6p25.3Cellular Component: transcription factor complex; nucleusMolecular Function: DNA binding; sequence-specific DNA binding; transcription factor binding; transcription factor activityBiological Process: genitalia development; extracellular matrix organization and biogenesis; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; epithelial to mesenchymal transition; positive regulation of transcription from RNA polymerase II promoter; embryonic camera-type eye morphogenesis; palate development; negative regulation of transcription, DNA-dependent; embryonic gut development; establishment of polarity of embryonic epithelium
UniProt Protein Details:
NCBI Summary:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. [provided by RefSeq, Jul 2008]
