The FOXG1 Antibody (CAB16851) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific to human FOXG1 samples and is validated for use in various applications, including Western blot and immunohistochemistry.FOXG1 is essential for proper brain development, regulating the expression of genes necessary for neuronal growth and function. Mutations in the FOXG1 gene are associated with neurological disorders, making it a target of interest for researchers studying neurodevelopmental diseases such as Rett Syndrome and autism spectrum disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
FOXG1 Antibody
SKU:
CAB16851
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:
YFTH QNQG SSSN PLIH
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
293T, SH-SY5Y, Mouse brain, Mouse spleen, Rat brain
Cellular Localization:
Nucleus.
Calculated MW:
52kDa
Observed MW:
52kDa
This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells.
Purification Method
Affinity purification
Gene ID
2290
RRID
AB_2769509
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using FOXG1 Rabbit pAb (CAB16851) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
