The GABARAP Polyclonal Antibody (CAB5616) is a valuable tool for research involving GABARAP, a protein involved in autophagy and intracellular trafficking processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the GABARAP protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in cell biology and neurodegenerative diseases.GABARAP plays a crucial role in autophagy, a cellular process essential for maintaining cellular homeostasis and eliminating damaged organelles or proteins.
Dysregulation of autophagy has been implicated in various diseases, including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. By studying the function of GABARAP, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets for intervention.
Product Name:
GABARAP Rabbit Polyclonal Antibody
SKU:
CAB5616
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human GABARAP (NP_009209.1).
Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
Purification Method:
Affinity purification
Gene ID:
11337
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABARAP Rabbit pAb (CAB5616) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
