The GAGE12i Polyclonal Antibody (PAC019690) is a valuable tool for research involving GAGE12i, a cancer-testis antigen known for its role in oncogenesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the GAGE12i protein, this antibody enables precise detection and analysis in various cell types, making it an excellent choice for studies in cancer biology and immunotherapy research.GAGE12i is a promising target for cancer research due to its restricted expression in cancerous tissues, making it a potential biomarker for cancer diagnosis and prognosis.
Its involvement in oncogenesis and tumor progression highlights its significance in understanding cancer biology and developing targeted therapies. The GAGE12i Polyclonal Antibody is an essential tool for investigating the functional role of GAGE12i in cancer development and exploring its potential as a therapeutic target in cancer treatment strategies.
Antibody Name:
GAGE12I Antibody (PACO19690)
Antibody SKU:
PACO19690
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human GAGE12I
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19690(GAGE12I Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19690(GAGE12I Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes.
Synonyms:
G antigen 12I
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
