The GC1q R/C1QBP Monoclonal Antibody (CAB11292) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has been extensively validated for use in various applications, such as immunohistochemistry and flow cytometry, and shows minimal cross-reactivity with other proteins.GC1q-R is known to play a crucial role in the activation of the complement system and can modulate immune responses by regulating the clearance of apoptotic cells and immune complexes. Dysregulation of GC1q-R has been linked to various autoimmune diseases and inflammatory conditions, making it an important target for therapeutic interventions.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GC1q R/C1QBP Monoclonal Antibody
SKU:
CAB11292
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC2753
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.
Purification Method
Affinity purification
Gene ID
708
RRID
AB_2861541
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using GC1q R/C1QBP Rabbit mAb (CAB11292) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using GC1q R/C1QBP Rabbit mAb (CAB11292) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Human colon carcinoma tissue using GC1q R/C1QBP Rabbit mAb (CAB11292) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Rat kidney tissue using GC1q R/C1QBP Rabbit mAb (CAB11292) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Mouse kidney tissue using GC1q R/C1QBP Rabbit mAb (CAB11292) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
