The GCC1 Antibody (PAC039274) is a polyclonal antibody specifically designed for research involving the Golgi coiled-coil protein 1 (GCC1). The antibody, produced through immunization of rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot analysis. By binding to the GCC1 protein, this antibody allows for the detection and analysis of GCC1 in different cell types, making it an ideal tool for studies in cell biology and molecular biology.GCC1 is a crucial protein involved in the regulation of Golgi structure and function, playing a key role in intracellular trafficking and protein sorting. Research on GCC1 can provide insights into Golgi-related processes and their implications in cellular function and disease development.
By studying GCC1, researchers can further understand the mechanisms underlying protein transport and trafficking, as well as their relevance in various pathological conditions.Given the importance of Golgi function in cellular processes, the GCC1 Antibody (PAC039274) represents a valuable tool for investigating GCC1 and its role in cellular biology. Its high reactivity and specificity make it a reliable choice for researchers studying Golgi dynamics, protein trafficking, and related cellular mechanisms. By utilizing this antibody, scientists can advance their understanding of Golgi biology and its impact on cellular homeostasis and disease progression.
Western blot. All lanes: GCC1 antibody at 2µg/ml. Lane 1: Hela whole cell lysate. Lane 2: 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 88 kDa. Observed band size: 88 kDa.
Immunohistochemistry of paraffin-embedded human breast cancer using PACO39274 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO39274 at dilution of 1:100.
Background:
Probably involved in maintaining Golgi structure.
Synonyms:
GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1), GCC1
UniProt Protein Function:
GCC1: Probably involved in maintaining Golgi structure.Protein type: VesicleChromosomal Location of Human Ortholog: 7q32.1Cellular Component: cytoplasm; cytosol; Golgi apparatus; plasma membraneMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008]
