The GCNT7 Polyclonal Antibody (PAC023796) is a valuable tool for researchers studying GCNT7, a glycosyltransferase enzyme involved in the biosynthesis of mucin-type O-glycans. This antibody, generated in rabbits, demonstrates high specificity towards human samples and is validated for use in Western blotting applications. By binding to the GCNT7 protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for investigations in glycobiology and cancer research.
GCNT7 plays a crucial role in the post-translational modification of glycoproteins, specifically in the addition of N-acetylglucosamine to O-linked glycans. Dysregulation of GCNT7 expression has been implicated in various diseases, including cancer and inflammatory disorders. Therefore, studying the function of GCNT7 and its impact on glycosylation patterns is essential for understanding disease mechanisms and developing targeted therapies.
GCNT7: Glycosyltransferase. Belongs to the glycosyltransferase 14 family.Protein type: EC 2.4.1.-; Transferase; Membrane protein, integralChromosomal Location of Human Ortholog: 20q13.2
