The GDPD5 Polyclonal Antibody (PAC015549) is a valuable tool for researchers studying GDPD5, a crucial enzyme involved in lipid metabolism and phospholipid biosynthesis. This antibody, produced in rabbits, has been specifically validated for use in Western blot applications and is highly reactive with human samples.GDPD5 plays a key role in cell membrane remodeling and lipid signaling pathways, making it an important target for research in fields such as lipid metabolism, cancer biology, and neurobiology. By detecting and analyzing the GDPD5 protein in various cell types, this antibody enables researchers to better understand its function and potential implications in disease settings.
With its high specificity and sensitivity, the GDPD5 Polyclonal Antibody is an essential tool for investigating the role of GDPD5 in various cellular processes and disease states. Its use in research may lead to new insights and potential therapeutic strategies for conditions related to lipid metabolism and phospholipid signaling.
Antibody Name:
GDPD5 Antibody (PACO15549)
Antibody SKU:
PACO15549
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:5000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human GDPD5
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8+15%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse pancreas tissue, human fetal brain tissue, Primary antibody: PACO15549(GDPD5 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
Background:
Glycerophosphodiester phosphodiesterases, such as GDPD5, are involved in glycerol metabolism. Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
GDPD5: Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine. Belongs to the glycerophosphoryl diester phosphodiesterase family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Phosphodiesterase; Membrane protein, multi-pass; EC 3.1.-.-Chromosomal Location of Human Ortholog: 11q13.4-q13.5Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]
