The GEMIN6 Antibody (CAB12375) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits strong reactivity towards human samples and has been validated for use in Western blot applications. By binding to the Gemin6 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in molecular biology and gene expression regulation.Gemin6 is a key player in the spliceosome complex, essential for proper mRNA processing and gene expression. Dysregulation of Gemin6 has been linked to various diseases, including spinal muscular atrophy and other neurodegenerative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
GEMIN6 Antibody
SKU:
CAB12375
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GEMIN6
Positive Sample:
HT-29, HeLa, 293T
Cellular Localization:
Cytoplasm, Nucleus, Gem, Nucleoplasm.
Calculated MW:
19kDa
Observed MW:
19kDa
GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).
Purification Method
Affinity purification
Gene ID
79833
RRID
AB_2759219
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GEMIN6 Rabbit pAb (CAB12375) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
