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GenieFluor 488 Anti-Human CD203c Antibody [NP4D6] (AGEL3400)

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SKU AGEL3400
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, k
Clone NP4D6
Conjugation AF488
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Description

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GenieFluor 488 Anti-Human CD203c Antibody [NP4D6]

The GenieFluor 488 Anti-Human CD203c Antibody (NP4D6) from Assay Genie is a highly specific and sensitive antibody designed for research targeting CD203c, a cell surface marker associated with mast cells and basophils. This monoclonal antibody, validated for use in flow cytometry and immunofluorescence applications, effectively detects and quantifies CD203c expression in human samples.CD203c is a key enzyme found on the surface of mast cells and basophils, playing a crucial role in allergic reactions and inflammatory responses.

By targeting CD203c, researchers can gain insights into the activation and function of these immune cells, paving the way for advancements in allergy research, immunology, and inflammatory disease studies. The GenieFluor 488 Anti-Human CD203c Antibody offers researchers a powerful tool for investigating the role of CD203c in various cellular processes and disease pathways.

Product Title:GenieFluor 488 Anti-Human CD203c Antibody [NP4D6]
SKU:AGEL3400
Size:20 Tests, 100 Tests, 200 Tests
Clone No:NP4D6
Synonyms:E-NPP3; ENPP3;PD-Ibeta;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:O14638
Gene ID:5169 
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD203c, a transmembrane protein and a member of the ectoenzyme family, is involved in the hydrolysis of extracellular oligonucleotides, nucleoside phosphates, and NAD (possesses ATPase and ATP pyrophosphatase activity). The molecular weight of CD203c is between 130 and 150 kD under reducing conditions and 270 kD under non-reducing conditions. CD203c is expressed on basophils and mast cells, and is highly expressed on activated basophils. Secretory glands in endometrium and glioma cells are also positive. CD203c is a multifunctional ectoenzyme involved in the clearance of extracellular nucleotides whose substrates include nucleoside triphosphates, nucleoside diphosphates, cAMP, and NAD.

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