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GenieFluor 488 Anti-Mouse CD45.2 Antibody [104.2] (AGEL2240)

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SKU AGEL2240
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Mouse
Isotype Mouse IgG2a, κ
Clone 104.2
Conjugation AF488
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Description

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GenieFluor 488 Anti-Mouse CD45.2 Antibody [104.2]

The Genie Fluor 488 Anti-Mouse CD45.2 Antibody (104-2) is a vital tool for research involving mouse CD45.2, a cell surface molecule essential for immune cell identification and function. This antibody, specifically designed for use in mouse samples, is highly sensitive and offers reliable performance in a variety of applications, including flow cytometry and immunofluorescence.CD45.2, a member of the protein tyrosine phosphatase family, is a key marker for distinguishing immune cell subsets in mice. Its role in immune cell activation and regulation makes it a crucial target for studying immune responses in various experimental settings, from basic immunology research to disease models.

By specifically binding to CD45.2, this antibody allows for precise detection and analysis of immune cells expressing this marker, facilitating detailed investigation into immune cell populations and their functions.The Genie Fluor 488 Anti-Mouse CD45.2 Antibody (104-2) is an indispensable tool for researchers looking to explore the complex interactions of immune cells in mouse models. With its high specificity and sensitivity, this antibody enables accurate and detailed analysis of CD45.2-expressing cells, paving the way for deeper insights into immune function and response mechanisms in diverse research fields, including immunology, infectious diseases, and autoimmune disorders.

Product Title:GenieFluor 488 Anti-Mouse CD45.2 Antibody [104.2]
SKU:AGEL2240
Size:50 Tests, 100 Tests, 200 Tests
Clone No:104.2
Synonyms:Ly-5.2; LCA;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 488 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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