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Key Features

GenieFluor 647 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL2171)

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SKU AGEL2171
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone M1/70
Conjugation AF647
€40 - €108
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Description

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GenieFluor 647 Anti-Mouse/Human CD11b Antibody [M1/70]

The GenieFluorâ„¢ 647 Anti-Mouse/Human CD11b Antibody (M1/70) offered by AssayGenie is a cutting-edge tool designed for researchers studying CD11b, a crucial cell surface marker involved in immune response regulation. This antibody, developed for use in both mouse and human samples, is specifically engineered to exhibit high reactivity and specificity for CD11b, enabling accurate detection and analysis in a variety of cell types.CD11b, a key integrin molecule, plays a vital role in mediating cellular adhesion and migration, particularly in the context of inflammation and immune system function. By targeting CD11b, researchers can gain valuable insights into the mechanisms underlying immune cell interactions and responses, paving the way for advancements in immunology, inflammation research, and related fields.

With its validated performance in various applications, including immunofluorescence and flow cytometry, the GenieFluorâ„¢ 647 Anti-Mouse/Human CD11b Antibody (M1/70) offers researchers a reliable tool for investigating the role of CD11b in health and disease. Whether studying immune cell behavior in cancer, infection, or inflammatory conditions, this antibody provides a versatile and sensitive means to explore CD11b expression and function, opening new avenues for scientific discovery.

Product Title:GenieFluor 647 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL2171
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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