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GenieFluor 647 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7] (AGEL2353)

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SKU AGEL2353
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, κ
Clone D7
Conjugation AF647
€75 - €203
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Description

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GenieFluor 647 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]

The GenieFluor 647 Anti-Mouse LY6A/E (Sca-1) Antibody (D7) (AGEL2353) is a powerful tool for researchers studying the LY6A/E (Sca-1) antigen in mouse samples. This antibody, developed by Assay Genie, is specifically designed to target and detect LY6A/E (Sca-1), a cell surface protein known for its role in stem cell and immune cell identification.With high specificity and sensitivity, the GenieFluor 647 Anti-Mouse LY6A/E (Sca-1) Antibody (D7) allows for precise detection and visualization of LY6A/E (Sca-1) in various cell types and tissues. Its compatibility with fluorescence microscopy and flow cytometry techniques makes it a versatile tool for immunology and stem cell research.

LY6A/E (Sca-1) is a marker that has been widely used in identifying stem cells, particularly in the hematopoietic system. Its expression pattern and function in immune responses have made it a key target for investigation in various research areas, including developmental biology, cancer biology, and regenerative medicine.By utilizing the GenieFluor 647 Anti-Mouse LY6A/E (Sca-1) Antibody (D7), researchers can further explore the functional roles of LY6A/E (Sca-1) in different biological processes and diseases, opening new avenues for understanding stem cell biology and immune modulation in mouse models.

Product Title:GenieFluor 647 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:AGEL2353
Size:50 Tests, 100 Tests, 200 Tests
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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