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GenieFluor 647 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7] (AGEL2359)

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SKU AGEL2359
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, κ
Clone D7
Conjugation AF647
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Description

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GenieFluor 647 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]

The GenieFluor 647 Anti-Mouse Ly-6A/E (Sca-1) Antibody (D7) (AGEL2359) offered by Assay Genie is a cutting-edge tool designed for research applications involving mouse Ly-6A/E, also known as Sca-1. This antibody, manufactured with high precision and specificity, targets the Ly-6A/E protein in mouse samples and is validated for use in various experimental techniques, including immunofluorescence and flow cytometry.Ly-6A/E, a cell surface marker linked to stem cell activity and differentiation, is a key player in various biological processes, including stem cell research, immunology, and regenerative medicine. The GenieFluor 647 Anti-Mouse Ly-6A/E (Sca-1) Antibody (D7) enables accurate detection and visualization of Ly-6A/E in different cell populations, allowing researchers to analyze and characterize these cells with precision and efficiency.

With its exceptional specificity and reliability, this antibody is a valuable tool for scientists exploring stem cell biology, tissue regeneration, and immune system dynamics in mouse models. By facilitating the study of Ly-6A/E-expressing cells, this antibody opens up new avenues for understanding cell behaviors, identifying stem cell populations, and investigating the role of Ly-6A/E in various biological contexts.

Product Title:GenieFluor 647 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:AGEL2359
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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