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Key Features

GenieFluor 647 Anti-Mouse Perforin Antibody [S16009A] (AGEL3309)

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SKU AGEL3309
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications ICFCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, k
Clone S16009A
Conjugation AF647
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Description

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GenieFluor 647 Anti-Mouse Perforin Antibody [S16009A]

The GenieFluor 647 Anti-Mouse Perforin Antibody (S16009A-AGEL3309) is a powerful tool designed for researchers studying perforin, a key protein involved in the immune response against infected or abnormal cells. This antibody, optimized for use in mouse samples, is produced to a high standard, ensuring reliable and specific detection of perforin in various experimental settings.Perforin is a crucial component of the immune system, playing a central role in the cytotoxic activity of T cells and natural killer cells. By binding specifically to perforin, this antibody allows for the precise visualization and quantification of this protein in different cell types and tissue samples.

Its application extends to a wide range of research fields, including immunology, cancer biology, and infectious diseases, where understanding perforin function is essential for unraveling the mechanisms of host defense and immune-mediated pathologies.With its superior performance and specificity, the GenieFluor 647 Anti-Mouse Perforin Antibody (S16009A-AGEL3309) is a valuable asset for scientists seeking to deepen their understanding of immune responses, cytotoxic processes, and the role of perforin in health and disease.

Product Title:GenieFluor 647 Anti-Mouse Perforin Antibody [S16009A]
SKU:AGEL3309
Size:50 Tests, 100 Tests, 200 Tests
Clone No:S16009A
Synonyms:Prf1; Pfp; Pfn; Pfn-1;Cytolysin;Lymphocyte pore-forming protein;
Host Species:Rat
Reactivity:Mouse
Application:ICFCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P10820
Gene ID:18646 
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.

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