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GenieFluor Red 780 Anti-Mouse CD80 Antibody [16-10A1] (AGEL3055)

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SKU AGEL3055
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Armenian Hamster
Isotype Armenian Hamster IgG
Clone 16-10A1
Conjugation AFRed 780
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Description

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GenieFluor Red 780 Anti-Mouse CD80 Antibody [16-10A1]

The GenieFluor Red 780 anti-mouse CD80 Antibody (16-10A1) (AGEL3055) offered by AssayGenie is a cutting-edge tool for researchers studying immune responses in mice. This antibody is specifically designed to target CD80, a key cell surface protein involved in regulating immune activation and T cell function. Developed for use in fluorescence-based assays, the GenieFluor Red 780 anti-mouse CD80 Antibody (16-10A1) (AGEL3055) provides precise and reliable detection of CD80 in various experimental settings. With its high specificity and sensitivity, it enables researchers to accurately analyze the expression and localization of CD80 in mouse cells and tissues.

By targeting CD80, researchers can gain valuable insights into the immune responses and regulatory mechanisms involved in inflammation, autoimmune diseases, and infection. The GenieFluor Red 780 anti-mouse CD80 Antibody (16-10A1) (AGEL3055) is a powerful tool that can enhance studies in immunology, oncology, and immunotherapy, ultimately contributing to the development of novel treatments and therapies for immune-related disorders.

Product Title:GenieFluor Red 780 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL3055
Size:50 Tests, 100 Tests, 200 Tests
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor Red 780 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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