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GenieFluor Red 780 Anti-Mouse CD80 Antibody [16-10A1] (AGEL3114)

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SKU AGEL3114
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Armenian Hamster
Isotype Armenian Hamster IgG
Clone 16-10A1
Conjugation AFRed 780
€113 - €300
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Description

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GenieFluor Red 780 Anti-Mouse CD80 Antibody [16-10A1]

The GenieFluor Red 780 Anti-Mouse CD80 Antibody (16-10A1) is a high-quality monoclonal antibody specifically designed for research involving CD80, a critical co-stimulatory molecule in the immune system. This antibody, produced by AssayGenie, is highly specific and provides reliable detection and analysis of CD80 protein in mouse samples.CD80, also known as B7-1, is essential for T cell activation and cytokine production, playing a vital role in the regulation of immune responses. The GenieFluor Red 780 Anti-Mouse CD80 Antibody is ideal for studies in immunology and related fields, allowing researchers to investigate the function and expression of CD80 in different cell types and experimental conditions.

This antibody is validated for use in various applications, including flow cytometry, immunofluorescence, and immunohistochemistry, providing flexibility for different research needs. By enabling precise and sensitive detection of CD80, researchers can gain insights into the role of this molecule in immune regulation, infection, autoimmune diseases, and other conditions where immune response modulation is crucial.For researchers looking to explore the intricate mechanisms of the immune system and develop targeted therapies, the GenieFluor Red 780 Anti-Mouse CD80 Antibody offers a valuable tool for advancing their scientific investigations.

Product Title:GenieFluor Red 780 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL3114
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor Red 780 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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