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GenieFluor Violet 450 Anti-Human CD20 Antibody [2H7] (AGEL3090)

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SKU AGEL3090
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, κ
Clone 2H7
Conjugation AFViolet 450
€107 - €413
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Description

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GenieFluor Violet 450 Anti-Human CD20 Antibody [2H7]

The GenieFLuor Violet 450 Anti-Human CD20 Antibody (2H7) from AssayGenie is a powerful tool for researchers studying CD20, a cell surface protein predominantly found on B cells. This antibody, validated for use in flow cytometry and immunofluorescence applications, specifically targets the CD20 protein, facilitating precise detection and analysis in human samples.CD20 is a well-known marker for B cell identification and targeting in various research areas, including immunology, oncology, and autoimmune diseases. The GenieFLuor Violet 450 Anti-Human CD20 Antibody (2H7) offers exceptional specificity and sensitivity, making it an essential reagent for investigating B cell biology, immune responses, and therapeutic interventions targeting CD20-positive cells.

With its reliable performance and versatility, this antibody is a valuable asset for scientists seeking to unravel the complexities of CD20 biology and its implications in health and disease. Unlock new insights into B cell function and explore the potential applications of targeting CD20 with the GenieFLuor Violet 450 Anti-Human CD20 Antibody (2H7) from AssayGenie.

Product Title:GenieFluor Violet 450 Anti-Human CD20 Antibody [2H7]
SKU:AGEL3090
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2H7
Synonyms:Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

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