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GenieFluor Violet 450 Anti-Human CD32 Antibody [IV-3] (AGEL3231)

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SKU AGEL3231
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, k
Clone IV-3
Conjugation AFViolet 450
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Description

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GenieFluor Violet 450 Anti-Human CD32 Antibody [IV-3]

The GenieFluor Violet 450 Anti-Human CD32 Antibody (IV.3) offered by AssayGenie is a powerful tool for researchers studying human CD32, a cell surface protein crucial in immune responses. This monoclonal antibody, specifically targeting human samples, is ideal for a range of immunological studies including flow cytometry, immunofluorescence, and immunohistochemistry applications.CD32, also known as Fc-gamma receptor II, is a key player in immune cell signaling and regulation, particularly in processes like phagocytosis and antibody-dependent cellular cytotoxicity.

By targeting CD32, researchers can delve into its role in inflammatory responses, autoimmune diseases, and infectious conditions. The GenieFluor Violet 450 Anti-Human CD32 Antibody provides accurate and reliable detection of CD32 protein expression in various cell types, aiding in the understanding of immune system functions and potential therapeutic interventions related to CD32 modulation.

Product Title:GenieFluor Violet 450 Anti-Human CD32 Antibody [IV-3]
SKU:AGEL3231
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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