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GenieFluor Violet 450 Anti-Mouse CD3 Antibody [17A2] (AGEL2957)

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SKU AGEL2957
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone 17A2
Conjugation AFViolet 450
€100 - €238
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Description

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GenieFluor Violet 450 Anti-Mouse CD3 Antibody [17A2]

The GenieFluor Violet 450 Anti-Mouse CD3 Antibody (17A2) is a powerful tool for research applications involving the CD3 protein, a crucial component of the T-cell receptor complex. This antibody, designed for mouse samples, is optimized for flow cytometry and immunofluorescence techniques, providing reliable and specific detection of CD3-expressing cells in various experimental settings.CD3 is essential for T-cell activation and function, making it a central target in immunology research.

By specifically binding to CD3, the GenieFluor Violet 450 Anti-Mouse CD3 Antibody enables precise visualization and analysis of T-cell populations, aiding in the investigation of immune responses, T-cell development, and immune-related diseases. Its high sensitivity and specificity ensure accurate and reproducible results in diverse research applications, making it an invaluable tool for scientists studying T-cell biology and immunotherapy.

Product Title:GenieFluor Violet 450 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL2957
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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