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GenieFluor Violet 450 Anti-Mouse F4/80 Antibody [CI:A3-1] (AGEL2946)

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SKU AGEL2946
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone CI:A3-1
Conjugation AFViolet 450
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Description

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GenieFluor Violet 450 Anti-Mouse F4/80 Antibody [CI:A3-1]

The GenieFluor Violet 450 Anti-Mouse F4/80 Antibody (CI:A3-1) is a powerful tool for researchers studying immune cells in mice. This antibody, specifically designed for use in flow cytometry and immunofluorescence applications, targets the F4/80 protein expressed on the surface of murine macrophages. With its high specificity and sensitivity, researchers can confidently detect and analyze macrophage populations in various tissues and experimental models.F4/80 is a well-known marker for murine macrophages, playing a crucial role in immune responses, tissue homeostasis, and inflammation. By utilizing the GenieFluor Violet 450 Anti-Mouse F4/80 Antibody, researchers can gain valuable insights into the function and dynamics of macrophages in different physiological and pathological contexts.

This antibody's exceptional performance and reproducibility make it an essential tool for studies focusing on immunology, inflammation, infectious diseases, and cancer research.By leveraging the GenieFluor Violet 450 Anti-Mouse F4/80 Antibody (CI:A3-1), researchers can advance their understanding of macrophage biology and the intricate mechanisms underlying immune responses in mice. This antibody is a reliable ally for in-depth explorations into the role of macrophages in health and disease, ultimately paving the way for potential therapeutic interventions and improved treatments.

Product Title:GenieFluor Violet 450 Anti-Mouse F4/80 Antibody [CI:A3-1]
SKU:AGEL2946
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CI:A3-1
Synonyms:Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q61549
Gene ID:13733
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

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