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GenieFluor Violet 450 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL2987)

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SKU AGEL2987
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone RB6-8C5
Conjugation AFViolet 450
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Description

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GenieFluor Violet 450 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The GenieFluor Violet 450 Anti-Mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) - AGEL2987 is a highly specific antibody designed for research in mouse models targeting the Ly-6G/Ly-6C (GR-1) antigen. This antibody, produced for laboratory use, has been optimized for applications such as flow cytometry and immunofluorescence, enabling precise detection and analysis of Ly-6G/Ly-6C-expressing cells in various research settings.Ly-6G and Ly-6C antigens are commonly used as markers for identifying and characterizing subpopulations of immune cells in mice, particularly neutrophils and monocytes. By targeting these specific antigens with the RB6-8C5 antibody, researchers can gain insights into the role of these cells in processes such as inflammation, immune response, and infection.

The GenieFluor Violet 450 Anti-Mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) - AGEL2987 is a valuable tool for immunology research, offering high sensitivity and specificity in detecting Ly-6G/Ly-6C-expressing cells. Its application extends to studies on inflammation, infection, and immune cell dynamics in mouse models, providing researchers with a powerful reagent for investigating immune responses and disease pathologies.

Product Title:GenieFluor Violet 450 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL2987
Size:25µg, 100µg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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