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GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL2943)

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SKU AGEL2943
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone M5/114
Conjugation AFViolet 450
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Description

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GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody (M5/114) (AGEL2943) is a highly specific antibody designed for research applications involving the detection and analysis of Mouse Major Histocompatibility Complex Class II molecules, specifically the I-A and I-E subtypes. This antibody, raised against mouse samples, is optimized for use in flow cytometry and immunofluorescence assays, allowing for precise visualization and quantification of MHC II expression on a variety of cell types.MHC II molecules play a crucial role in the immune system by presenting antigens to T-cells, thereby initiating and regulating immune responses. The M5/114 antibody is essential for studying MHC II antigen presentation pathways, immune cell activation, and immune response modulation in various experimental settings.

Its high specificity and sensitivity make it an invaluable tool for researchers in immunology, vaccine development, and autoimmune disease studies.With its ability to specifically target Mouse MHC II (I-A/I-E) molecules, the GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody (M5/114) (AGEL2943) offers precise and reliable results, making it a must-have reagent for laboratories conducting cutting-edge research in the fields of immunology, vaccine development, and immunotherapy.

Product Title:GenieFluor Violet 450 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL2943
Size:25µg, 100µg
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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