Description
GHITM Antibody (PACO03879)
The GITM Antibody (PAC03879) is a reliable tool for researchers studying the GITM protein, which is known to be involved in immune regulation and inhibiting immune responses. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding to the GITM protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.The GITM protein, also referred to as an immune inhibitory receptor, plays a crucial role in maintaining immune balance by controlling inflammation and suppressing allergic reactions.
Its role in immune response modulation positions it as a valuable target for investigations into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Comprehensive knowledge of GITM protein activity is essential for the development of therapies that manipulate or regulate immune function within these disease contexts.
| Antibody Name: | GHITM Antibody |
| Antibody SKU: | PACO03879 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human GHITM. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GHITM; DERP2; MICS1; TMBIM5; My021; Growth hormone-inducible transmembrane protein; Dermal papilla-derived protein 2; Mitochondrial morphology and cristae structure 1; MICS1; Transmembrane BAX inhibitor motif-containing protein 5 |
| UniProt Protein Function: | GHITM: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. Belongs to the BI1 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 10q23.1 Cellular Component: integral to membrane; mitochondrial inner membrane Molecular Function:protein binding Biological Process: apoptosis |
| UniProt Code: | Q9H3K2 |
| NCBI GenInfo Identifier: | 15213977 |
| NCBI Gene ID: | 27069 |
| NCBI Accession: | Q9H3K2.2 |
| UniProt Secondary Accession: | Q9H3K2,O95894, Q5VT95, Q9H0P2, A8K9Z9, D3DWE0, |
| UniProt Related Accession: | Q9H3K2 |
| Molecular Weight: | 37,205 Da |
| NCBI Full Name: | Growth hormone-inducible transmembrane protein |
| NCBI Synonym Full Names: | growth hormone inducible transmembrane protein |
| NCBI Official Symbol: | GHITMÂ Â |
| NCBI Official Synonym Symbols: | DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282Â Â |
| NCBI Protein Information: | growth hormone-inducible transmembrane protein |
| UniProt Protein Name: | Growth hormone-inducible transmembrane protein |
| UniProt Synonym Protein Names: | Dermal papilla-derived protein 2; Mitochondrial morphology and cristae structure 1; MICS1; Transmembrane BAX inhibitor motif-containing protein 5 |
| Protein Family: | Growth hormone-inducible transmembrane protein |
| UniProt Gene Name: | GHITMÂ Â |
| UniProt Entry Name: | GHITM_HUMAN |
