The GJA4 Antibody (CAB2529) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the GJA4 protein, this antibody allows for the detection and analysis of connexin 37 in various cell types, making it ideal for investigations in cardiovascular and vascular biology.Connexin 37 is a crucial component of gap junction channels, which play a key role in intercellular communication in the vascular system. Dysregulation of connexin 37 has been implicated in various cardiovascular diseases, making it a promising target for research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.
Product Name:
GJA4 Antibody
SKU:
CAB2529
Size:
20μL, 100μL
Reactivity:
Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CX37, GJA4
Positive Sample:
Rat liver,
Cellular Localization:
Cell Junction, Cell Membrane, Multi-Pass Membrane Protein, Gap Junction.
Calculated MW:
37kDa
Observed MW:
37kDa
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.
Purification Method
Affinity purification
Gene ID
2701
RRID
AB_2764420
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Rat liver using GJA4 Rabbit pAb (CAB2529) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
